Pkd1 is required for male reproductive tract development
نویسندگان
چکیده
منابع مشابه
Pkd1 is required for male reproductive tract development
Reproductive tract abnormalities and male infertility have higher incidence in ADPKD patients than in general populations. In this work, we reveal that Pkd1, whose mutations account for 85% of ADPKD cases, is essential for male reproductive tract development. Disruption of Pkd1 caused multiple organ defects in the murine male reproductive tract. The earliest visible defect in the Pkd1(-/-) repr...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2013
ISSN: 0925-4773
DOI: 10.1016/j.mod.2013.07.006